polymorphic variant造句

例句与造句

1. polymorphic variants commonly produced enzymes that functioned in a dominant negative manner, leading to lack of SIAE enzymatic activities.
2. Polymorphic variants and a reciprocal translocation t ( 6; 8 ) ( q26; q13 ) involving this gene, have been associated with Duane retraction syndrome.
3. For instance : white-faced capuchin monkeys ( " polymorphic variants, red lizards have are more aggressive in defending their territory compared to their yellow counterparts.
4. AXIS inhibition protein 2 ( AXIN2 ) gene polymorphic variants may be associated with both hypodontia and oligodontia ( characterized by the lack of six or more permanent teeth ).
5. A polymorphic variant of a gene may lead to the abnormal expression or to the production of an abnormal form of the gene; this may cause or be associated with disease.
6. It's difficult to find polymorphic variant in a sentence. 用polymorphic variant造句挺难的
7. His work on LOX-1 receptors, its polymorphic variants and its role in atherogenesis and myocardial ischemia has led to new therapeutic targets now being pursued by several biotech companies, such as MedImmune.
8. For example, a polymorphic variant of the enzyme CYP4A11 in which thymidine replaces cytosine at the gene's nucleotide 8590 position encodes a CYP4A11 protein that substitutes phenylalanine with serine at the protein's amino acid position 434.
9. Men without anomalies of spermatogenesis exhibit no hyper-methylation in the MTHFR promoter region, as the allele remains unmethylated and MTHFR is expressed . [ 5 ] Several studies have shown associations between polymorphic variants in the MTHFR promoter and reduced sperm counts.
10. Further assessment of EFS expression, mutational status, and potential polymorphic variants may be of use in understanding the biology and developing treatment strategies for immune system pathologies such as CHS . There are currently no therapeutic approaches targeting EFS, and given the protein lacks a catalytic domain and extracellular moieties, it may be challenging to generate such agents.
11. BRCA1 and BRCA2 polymorphic variants can increase the risk of breast cancer, and these cancers tend to express a pr ofile of genes, such as p53, in a pattern that has been called " BRCA-ness . " Cancers arising from BRCA1 and BRCA2 mutations, as well as other cancers that share a similar " BRCA-ness " profile, including some basal-like receptor triple negative breast cancers, may respond to treatment with PARP inhibitors such as olaparib.